Towards A Sustainable and Ethical Supply Chain Management: The Potential of IoT Solutions

Globalization has introduced many new challenges making Supply chain management (SCM) complex and huge, for which improvement is needed in many industries. The Internet of Things (IoT) has solved many problems by providing security and traceability with a promising solution for supply chain management. SCM is segregated into different processes, each requiring different types of solutions. IoT devices can solve distributed system problems by creating trustful relationships. Since the whole business industry depends on the trust between different supply chain actors, IoT can provide this trust by making the entire ecosystem much more secure, reliable, and traceable. This paper will discuss how IoT technology has solved problems related to SCM in different areas. Supply chains in different industries, from pharmaceuticals to agriculture supply chain, have different issues and require different solutions. We will discuss problems such as security, tracking, traceability, and warehouse issues. All challenges faced by independent industries regarding the supply chain and how the amalgamation of IoT with other technology will be provided with solutions.Comment: 9 page

Gray Image Colorization using Thepade’s Transform Error Vector Rotation With Cosine, Walsh, Haar Transforms and various Similarity Measures

The paper presents various gray image colorization methods based on vector quantization for performing automatic colorization. To colorize gray target image by extracting color pixels from source color image, Thepade’s Transform Error Vector Rotation vector quantization methods such as Thepade’s Cosine Error Vector Rotation (TCEVR), Thepade’s Walsh Error Vector Rotation (TWEVR) and Thepade’s Haar Error Vector Rotation (THEVR) are used along with varied similarity measures. The quality of colorization of gray image is subjective to the source color image and target gray image (to be colored). Here the image test bed of 25 images is used to recolor the gray equivalent of the original color images for qualitative performance comparison of proposed colorization methods with help of PSNR between original color and recolored images. Colorization is performed using diverse similarity measures which belong to different families. These nine similarity measures are used for mapping gray image pixels with relatively corresponding multichorme image pixels. When these similarity measures are assessed for their comparison for colorizing the target gray image, it is observed that Chebychev outruns all other similarity measures and the worst performance is consistently given by Jaccard and Hamming distances. Among all the considered colorization methods Thepade’s Haar Error Vector Rotation is much suitable algorithm for performing gray image colorization. DOI: 10.17762/ijritcc2321-8169.150516

Review of studies on thermal comfort in Indian residential buildings

This paper presents the systematic review on thermal comfort studies in Indian residential buildings, helpful in identifying the present research scenario, data gaps and policy interventions. Majority of the studies are performed in composite climate (ten), followed by warm-humid (seven) and a very few from cold (two) and hot-dry (two) climates. None of the thermal comfort study is found from temperate climate. Besides, the seven studies have considered multiple climates for assessment of thermal comfort in residential buildings. This shows that thermal comfort studies in Indian residential buildings are scarce, scattered and unorganized. Further, due to differences in socio-cultural set-up and local adaptations, the prodigious variations in occupant’s comfort requirements are reported. This review argues the dynamic modifications in individual behaviours due to change in cost of building energy services and comfort requirements. Only four studies have partially considered the occupant behaviour regarding control of indoor thermal environment. The results obtained from these studies indicate that there is strong need of localised thermal comfort model that will not only help in improving comfort requirements but also the building energy performance. Moreover, this review paves way for research development in India where high residential building stock is yet to be built

Medicalization of sexuality and sexual health: A perspective review

Sexuality has become a medical issue in the context of aging due to a variety of aspects, such as growing life expectancy, an optimistic societal paradigm that indorses sexuality as significant for the superiority of life with age, and the medicalization of sexuality with the emergence of remedial medicines to extravagance sexual dysfunction. At any age, a reduction in the desire for sexual activity or inadequate performance of sexual intercourse is considered atypical and requires a medicinal treatment response. However, despite concerns that this is leading to an unhealthy obsession with sexuality from a medical perspective, this line of thinking is likely to continue. In this context, people can identify and take advantage of sexual problems. Sexual desire and performance are affected by normal physiological changes associated with aging in both genders. Medical experts must understand these changes to optimize sexual functioning in older patients. Sexual health can only be improved by addressing both sexual rights and enjoyment, even in the current politically charged context. Through legislation, programming, and lobbying, we may all work to enhance health, happiness, and quality of life by fostering more positive associations between sexual health, sexual rights, and sexual pleasure. This calls for not just a thorough understanding of the real-world consequences of these ideas' interconnectivity, but also conceptual, individual, and systemic approaches that properly acknowledge and alleviate the problems imposed on people's lives due to insufficient consideration of these links. This review describes the factors associated with aging and sexuality, the normalization and medicalization of sexual health, and unusual situations associated with aging, including institutionalized care and the prospects of elder abuse

Genotyping of Cryptosporidium spp. isolated from young domestic ruminants in some targeted areas of India

Faecal samples (363) from kids, lambs, calves and buffalo calves of below 3 months of age were collected from various parts of India and screened microscopically for Cryptosporidium oocysts using modified Ziehl–Neelsen method of staining. Microscopically positive samples (20) were genotyped by PCR amplification of the partial 18S rRNA region and subsequent digestion by SspI, VspI and MboII restriction enzymes. Based on the PCR-RFLP patterns of 18S rRNA, all the 20 samples were found positive for C. parvum. All the positive samples were also used for amplification of partial actin gene of Cryptosporidium spp. For further confirmation of the species of Cryptosporidium, amplified 818 bp partial actin gene of 3 representative isolates was cloned and sequenced. The sequence and phylogenetic analysis of PCR-positive samples confirmed the presence of C. parvum. Thus, actin gene can also be used for specific molecular diagnosis of Cryptosporidium spp., in addition to 18S rRNA. These findings also indicated that young domestic ruminants can be a potent source of cryptosporidial infection for humans and animals in India

Cryptic Eimeria genotypes are common across the southern but not northern hemisphere

The phylum Apicomplexa includes parasites of medical, zoonotic and veterinary significance. Understanding the global distribution and genetic diversity of these protozoa is of fundamental importance for efficient, robust and long-lasting methods of control. Eimeria spp. cause intestinal coccidiosis in all major livestock animals and are the most important parasites of domestic chickens in terms of both economic impact and animal welfare. Despite having significant negative impacts on the efficiency of food production, many fundamental questions relating to the global distribution and genetic variation of Eimeria spp. remain largely unanswered. Here, we provide the broadest map yet of Eimeria occurrence for domestic chickens, confirming that all the known species (Eimeria acervulina, Eimeria brunetti, Eimeria maxima, Eimeria mitis, Eimeria necatrix, Eimeria praecox, Eimeria tenella) are present in all six continents where chickens are found (including 21 countries). Analysis of 248 internal transcribed spacer sequences derived from 17 countries provided evidence of possible allopatric diversity for species such as E. tenella (FST values ⩽0.34) but not E. acervulina and E. mitis, and highlighted a trend towards widespread genetic variance. We found that three genetic variants described previously only in Australia and southern Africa (operational taxonomic units x, y and z) have a wide distribution across the southern, but not the northern hemisphere. While the drivers for such a polarised distribution of these operational taxonomic unit genotypes remains unclear, the occurrence of genetically variant Eimeria may pose a risk to food security and animal welfare in Europe and North America should these parasites spread to the northern hemisphere

Gradient Descent Optimization in Gene Regulatory Pathways

BACKGROUND: Gene Regulatory Networks (GRNs) have become a major focus of interest in recent years. Elucidating the architecture and dynamics of large scale gene regulatory networks is an important goal in systems biology. The knowledge of the gene regulatory networks further gives insights about gene regulatory pathways. This information leads to many potential applications in medicine and molecular biology, examples of which are identification of metabolic pathways, complex genetic diseases, drug discovery and toxicology analysis. High-throughput technologies allow studying various aspects of gene regulatory networks on a genome-wide scale and we will discuss recent advances as well as limitations and future challenges for gene network modeling. Novel approaches are needed to both infer the causal genes and generate hypothesis on the underlying regulatory mechanisms. METHODOLOGY: In the present article, we introduce a new method for identifying a set of optimal gene regulatory pathways by using structural equations as a tool for modeling gene regulatory networks. The method, first of all, generates data on reaction flows in a pathway. A set of constraints is formulated incorporating weighting coefficients. Finally the gene regulatory pathways are obtained through optimization of an objective function with respect to these weighting coefficients. The effectiveness of the present method is successfully tested on ten gene regulatory networks existing in the literature. A comparative study with the existing extreme pathway analysis also forms a part of this investigation. The results compare favorably with earlier experimental results. The validated pathways point to a combination of previously documented and novel findings. CONCLUSIONS: We show that our method can correctly identify the causal genes and effectively output experimentally verified pathways. The present method has been successful in deriving the optimal regulatory pathways for all the regulatory networks considered. The biological significance and applicability of the optimal pathways has also been discussed. Finally the usefulness of the present method on genetic engineering is depicted with an example

Population, genetic, and antigenic diversity of the apicomplexan Eimeria tenella and their relevance to vaccine development

The phylum Apicomplexa includes serious pathogens of humans and animals. Understanding the distribution and population structure of these protozoan parasites is of fundamental importance to explain disease epidemiology and develop sustainable controls. Predicting the likely efficacy and longevity of subunit vaccines in field populations relies on knowledge of relevant preexisting antigenic diversity, population structure, the likelihood of coinfection by genetically distinct strains, and the efficiency of cross-fertilization. All four of these factors have been investigated for Plasmodium species parasites, revealing both clonal and panmictic population structures with exceptional polymorphism associated with immunoprotective antigens such as apical membrane antigen 1 (AMA1). For the coccidian Toxoplasma gondii only genomic diversity and population structure have been defined in depth so far; for the closely related Eimeria species, all four variables are currently unknown. Using Eimeria tenella, a major cause of the enteric disease coccidiosis, which exerts a profound effect on chicken productivity and welfare, we determined population structure, genotype distribution, and likelihood of cross-fertilization during coinfection and also investigated the extent of naturally occurring antigenic diversity for the E. tenella AMA1 homolog. Using genome-wide Sequenom SNP-based haplotyping, targeted sequencing, and single-cell genotyping, we show that in this coccidian the functionality of EtAMA1 appears to outweigh immune evasion. This result is in direct contrast to the situation in Plasmodium and most likely is underpinned by the biology of the direct and acute coccidian life cycle in the definitive host

Measurement of t(t)over-bar normalised multi-differential cross sections in pp collisions at root s=13 TeV, and simultaneous determination of the strong coupling strength, top quark pole mass, and parton distribution functions

Peer reviewe

Measurement of the top quark forward-backward production asymmetry and the anomalous chromoelectric and chromomagnetic moments in pp collisions at √s = 13 TeV

Abstract The parton-level top quark (t) forward-backward asymmetry and the anomalous chromoelectric (d̂ t) and chromomagnetic (μ̂ t) moments have been measured using LHC pp collisions at a center-of-mass energy of 13 TeV, collected in the CMS detector in a data sample corresponding to an integrated luminosity of 35.9 fb−1. The linearized variable AFB(1) is used to approximate the asymmetry. Candidate t t ¯ events decaying to a muon or electron and jets in final states with low and high Lorentz boosts are selected and reconstructed using a fit of the kinematic distributions of the decay products to those expected for t t ¯ final states. The values found for the parameters are AFB(1)=0.048−0.087+0.095(stat)−0.029+0.020(syst),μ̂t=−0.024−0.009+0.013(stat)−0.011+0.016(syst), and a limit is placed on the magnitude of | d̂ t| < 0.03 at 95% confidence level. [Figure not available: see fulltext.